Prostate Cancer Research
To learn more about prostate cancer and ongoing clinical trials in this area, visit our Prostate Cancer Research page.
Prostate Cancer ResearchThe purpose of this study is to evaluate how safe and effective abemaciclib is when given to participants whose metastatic prostate cancer progresses after they had received several previous treatments.
Participant must have diagnosis of prostate cancer that is metastatic
Participant must have prostate cancer for which castration (medical or surgical) is no longer effective (castration-resistant)
Participant must have documented evidence of progressive disease by imaging and/or PSA test
Participant must be willing to undergo a biopsy of tumor tissue (or able to provide adequate archived tumor tissue sample) and to provide blood for research
Participants must not have conditions that are not compatible with the clinical trial participation such as inability to swallow large pills, active or chronic liver disease, clinically significant heart disease, HIV, AIDS, active or uncontrolled clinically serious infection, or uncontrolled hypertension
Participant must not have brain metastases
Participant of reproductive potential must not father a child and must agree to use medically approved contraceptive precautions, and not donate sperm, during the study and for three months following the last dose of study drug
To learn more about prostate cancer and ongoing clinical trials in this area, visit our Prostate Cancer Research page.
Prostate Cancer ResearchTo learn more about the different types of cancer research we conduct and ongoing clinical trials, visit our Cancer Research page.
Learn MoreA clinical trial helps us learn if a new potential medicine or treatment works and how it works. Clinical trials are also called clinical research studies. To learn more about what to expect when taking part in a clinical trial, visit our Clinical Trial Information page.