Pain Research
To learn more about clinical trials for pain, visit our Pain Research page.
Learn MoreThe reason for this study is to see if the study drug LY3451838 is safe and effective in participants who have migraine that have not responded to other preventive treatments.
Participants must have a diagnosis of migraine or chronic migraine
Participants must have a history of migraine headaches at least 1 year prior to screening and that began prior to age 50
Participants must have failed previous migraine preventive medications in the past 10 years due to too little helpfulness or the ability to put up with the medication
Participants must not be currently enrolled in or have participated within the last 30 days or within 5 half-lives (whichever is longer) in a clinical trial involving an investigational product. A half-life is the time necessary for half of any drug in the body to be removed by natural processes
Participants must not have a history of daily headache, cluster headache, certain migraine subtypes, or other incompatible headache diagnoses
Participants must not be pregnant or nursing
To learn more about clinical trials for pain, visit our Pain Research page.
Learn MoreLearn how Lilly is working with health care partners to improve diversity in our clinical studies.
Watch the VideoA clinical trial helps us learn if a new potential medicine or treatment works and how it works. Clinical trials are also called clinical research studies. To learn more about what to expect when taking part in a clinical trial, visit our Clinical Trial Information page.