A Trial of Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab (PVR) Versus Venetoclax and Rituximab (VR) in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (BRUIN CLL-322)
This is a study for participants with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have already received treatment for this disease. The main purpose is to add pirtobrutinib to other drugs that have already been approved by the United States Food and Drug Administration (US FDA), and by many other countries, for CLL/SLL.
Trial Summary
Key Requirements
Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.Participants Must:
Have chronic lymphocytic leukemia or small lymphocytic lymphoma that requires treatment
Have already had treatment for this disease
Be well enough to perform their own personal care
Have adequate organ function and blood counts, as measured by blood tests
Participants Must Not:
Have cancer that has changed to different type of cancer or has spread to the brain or spinal cord
Have serious heart disease
Need a blood thinner called warfarin
Have any problems absorbing food or medicine taken by mouth
Take certain medicines that affect how fast the study drug is broken down in the body
Have active infection
Lilly Trial Alerts
Clinical Trial Resources
You will complete the questionnaire on another website.YesNo