A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 2 Diabetes Currently Treated With Basal Insulin (QWINT-3)

I8H-MC-BDCU -

The reason for this study is to see if the study drug insulin efsitora alfa (LY3209590) is safe and effective in participants with Type 2 diabetes that have already been treated with basal insulin.

Trial Summary

Age Range
≥18 years
Conditions the trial is for
Type 2 Diabetes
What the trial is testing?
LY3209590, Insulin Degludec, Insulin Efsitora Alfa
Could I receive a Placebo?
No
Enrollment Goal
986
Trial Dates
Mar 8, 2022 - May 15, 2024
How long will I be in the trial?
Your participation could last about 86 weeks and may include up to 39 visits to the study center.
Trial Phase
III

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Participants must have type 2 diabetes mellitus (T2DM)

  • Participants must be receiving basal insulin

  • Participants may be taking other medications to treat diabetes if they are allowed during the study

  • Acceptable non insulin glucose lowering therapies may include 0 to up to 3 of the following:

    • dipeptidyl peptidase (DPP-4) IV inhibitors

    • SGLT2 inhibitors

    • alphaglucosidase inhibitors or,

    • Glucagon-Like Peptide-1 (GLP-1) receptor agonist

  • Participants must be willing to stay on stable dose throughout the study

Participants Must Not:

  • Participants must not have type 1 diabetes mellitus (T1DM)

  • Participants must not have lost or gained weight in the last 3 months

  • Participants must not have known liver disease

Lilly Trial Alerts

Sign up to receive updates about new trials and find out when a clinical trial site near you starts enrolling.

Clinical Trial Resources

Diabetes Research

To learn more about diabetes and ongoing clinical trials in this area, visit our Diabetes Research page.

Clinical Trial Information

A clinical trial helps us learn if a new potential medicine or treatment works and how it works. Clinical trials are also called clinical research studies. To learn more about what to expect when taking part in a clinical trial, visit our Clinical Trial Information page.