Enrolling

A Study of LOXO-783 in Patients With Breast Cancer/Other Solid Tumors (PIKASSO-01)

J4C-OX-JZUA -

The main purpose of this study is to learn more about the safety, side effects, and effectiveness of LOXO-783. LOXO-783 may be used to treat breast cancer and other solid tumors that have a change in a particular gene (known as the PIK3CA gene).

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See if You May Qualify

Answer a few questions to see if you meet key criteria for this study.

Trial Summary

Age Range
≥18 years
Conditions the trial is for
Breast Cancer, Advanced Solid Tumors
What the trial is testing?
LOXO-783
Could I receive a Placebo?
No
Enrollment Goal
400
Trial Dates
May 11, 2022 - May 2025
How long will I be in the trial?
Your participation in this trial could last up to 36 months, depending on your cancer type and how you and your tumor respond.
Trial Phase
I

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Have advanced breast cancer or another cancer with a change in the PIK3CA gene

  • Have stopped all cancer treatment and have recovered from the major side effects

  • Have blood test results that show that organs are working adequately

  • Have a tumor that can be measured by imaging (for non-breast cancer patients) or has disease in the bones that cannot be measured by imaging (for breast cancer patients only)

Participants Must Not:

  • Have an active infection or any serious medical conditions (other than cancer)

  • Have cancer that has spread to the brain and is causing symptoms

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