A Study of Remternetug (LY3372993) in Participants With Alzheimer's Disease (TRAILRUNNER-ALZ 1)

The reason for this study is to collect safety and efficacy information regarding the study drug remternetug in participants with early Alzheimer's disease (AD).

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See if You May Qualify

Select a location and then answer a few questions or connect with the study site to see if you meet key criteria for this study.

Trial Summary

Age Range
60 - 85 years
Conditions the trial is for
Alzheimer's disease
What the trial is testing?
Remternetug (LY3372993)
Could I receive a Placebo?
Enrollment Goal
Trial Dates
Aug 1, 2022 - Oct 2026
How long will I be in the trial?
Your participation could last up to 2 years and may include up to 22 visits to the study center.
Trial Phase

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Participants must have a gradual and progressive change in memory or ability to think and function for more than 6 months prior to screening

  • Participants must have a reliable study partner

Participants Must Not:

  • Participants must not have significant disease affecting the brain other than Alzheimer's Disease (AD) that could interfere with this study

  • Participants must not have other serious illnesses that could interfere with this study

  • Participants must not have a history of severe drug allergies

  • Participants must not have certain health conditions that prevent them from getting an MRI or positron emission tomography (PET) scan

  • Participants must not have had recent prior treatment with a drug to remove plaque from the brain

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Clinical Trial Resources

Alzheimer’s Disease and Memory Loss Research Studies

To learn more about Alzheimer’s, memory loss and clinical trials being carried out in this area, visit our Alzheimer’s Disease Research page.

Learn More

Neurodegenerative Disease Research

To learn more about neurodegenerative diseases and clinical trials being carried out in the area, visit our Neurodegenerative Disease Research page.

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study. It helps us learn if a new medicine or treatment works and how it works. Clinical trials can also be called clinical research studies. Learn more about clinical research studies and what to expect when taking part in a clinical trial.