Completed Enrollment

A Study of Peresolimab (LY3462817) in Participants With Moderately-to-Severely Active Rheumatoid Arthritis (RESOLUTION-1)

J1A-MC-KDAF -

The main purpose of this study is to assess the safety and efficacy of peresolimab in adult participants with moderately-to-severely active rheumatoid arthritis.

Trial Summary

Age Range
≥18 years
Conditions the trial is for
Rheumatoid Arthritis
What the trial is testing?
Peresolimab
Could I receive a Placebo?
Yes
Enrollment Goal
491
Trial Dates
Aug 31, 2022 - Jan 2025
How long will I be in the trial?
The study will last about 78 weeks and may include up to 20 visits.
Trial Phase
II

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Have a diagnosis of adult onset rheumatoid arthritis for at least 3 months

Participants Must Not:

  • Had cancer within the last 5 years, except for some types of skin cancer or cervical cancer
  • Had cervical dysplasia
  • Had certain types of infections within the last 3 months
  • Have HIV
  • Have current hepatitis virus B or C infection

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Clinical Trial Resources

Rheumatoid Arthritis Research

By volunteering to take part in Rheumatoid Arthritis clinical trials, you may be able to play an important role in the research and development of potential new treatments and medicines. We understand that when you or a loved one take part in a clinical trial, it is a big decision. It is important for you to understand why the research is being carried out and what taking part will mean for you. Learn more about Lilly

Rheumatoid Arthritis Research

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Clinical Trial Participation: What to Expect

A clinical trial is a scientific study. It helps us learn if a new medicine or treatment works and how it works. Clinical trials can also be called clinical research studies. Learn more about clinical research studies and what to expect when taking part in a clinical trial.