A Study of LY3473329 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events (KRAKEN)

Participants must be at least 40 years old and have Lipoprotein(a) level≥175 nmol/L at screening

Have coronary artery disease, stroke or peripheral artery disease, familiar hypercholesterolemia or type 2 diabetes

Participants if on the following medications must be on stable regimen before participating and through the end of treatment and assessment period: lipid-lowering drugs, testosterone, estrogens, anti-estrogens, progestins, selective estrogen receptor modulators or growth hormone

Have body mass index within the range 18.5 to 40 kilogram/square meter

Males and female of child bearing potential who agree to use highly effective contraception methods or women not of childbearing age

Had history of underlying disease or surgical, physical medical or psychiatric condition

Had major surgery within 3 months of randomization

Had coronary, carotid, or peripheral arteria revascularization, stroke, heart attack or chest pain within 3 months of day 1

Have uncontrolled diabetes

Have uncontrolled high blood pressure