Enrolling

A Study of LY3540378 in Participants With Worsening Chronic Heart Failure With Preserved Ejection Fraction (HFpEF)

The main purpose of this study is to assess the efficacy and safety of LY3540378 in adults with worsening heart failure with preserved ejection fraction.

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See if You May Qualify

Answer a few questions to see if you meet key criteria for this study.

Trial Summary

Age Range
≥18 years
Conditions the trial is for
Heart Failure
What the trial is testing?
LY3540378
Could I receive a Placebo?
Yes
Enrollment Goal
432
Trial Dates
Feb 3, 2023 - Jan 2026
How long will I be in the trial?
The study will last about 32 weeks and may include up to 26 visits.
Trial Phase
II

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Have chronic heart failure

Participants Must Not:

  • Have heart transplant

  • Have uncontrolled irregular heart beats

  • Have heart failure triggered by blood clot in lungs

  • Have stroke

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Clinical Trial Resources

Cardiovascular (Heart Disease) Research

By volunteering to take part in Cardiovascular clinical trials, you may be able to play an important role in the research and development of potential new treatments and medicines. We understand that when you or a loved one take part in a clinical trial, it is a big decision. It is important for you to understand why the research is being carried out and what taking part will mean for you. Learn more about Lilly

Cardiovascular Research

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study. It helps us learn if a new medicine or treatment works and how it works. Clinical trials can also be called clinical research studies. Learn more about clinical research studies and what to expect when taking part in a clinical trial.