Immunology Research
To learn more about immune system conditions and ongoing clinical trials in this area, visit our Immunology Research page.
Learn MoreThe main purpose of this study is to evaluate the efficacy and safety of LY3857210 in participants with osteoarthritic pain. This trial is part of the chronic pain master protocol (H0P-MC-CPMP) which is a protocol to accelerate the development of new treatments for chronic pain.
Have a history of daily pain for at least 12 weeks
Participants must be willing to maintain any non-drug pain relieving therapies (for example, physical therapy) and not start any new non-drug pain-relieving therapies during the study
Are willing to discontinue all medications taken for chronic pain conditions throughout the study
Have knew pain for >12 weeks at screening
Have a siezure disorder or history of seizure
Have had a surgical procedure or therapeutic injection in the affected knee within 3 months prior to starting the washout period
Have presence of surgical hardware or other foreign body in the index knee.
Have a surgery planned during the study for any reason
Have had cancer within 2 years of baseline
To learn more about immune system conditions and ongoing clinical trials in this area, visit our Immunology Research page.
Learn MoreTo learn more about clinical trials for pain, visit our Pain Research page.
Learn MoreA clinical trial helps us learn if a new potential medicine or treatment works and how it works. Clinical trials are also called clinical research studies. To learn more about what to expect when taking part in a clinical trial, visit our Clinical Trial Information page.