A Study of Mirikizumab (LY3074828) in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT-URGE)

A study to investigate bowel urgency in adults with moderately to severely active ulcerative colitis treated with mirikizumab. The study will have 4 periods.

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See if You May Qualify

Answer a few questions to see if you meet key criteria for this study.

Trial Summary

Age Range
≥18 years
Conditions the trial is for
Ulcerative Colitis
What the trial is testing?
Could I receive a Placebo?
Enrollment Goal
Trial Dates
May 17, 2023 - Mar 2025
How long will I be in the trial?
The study will last approximately 36 weeks and include up to 11 visits.
Trial Phase

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Have ulcerative colitis (chronic inflammation)

  • Have bowel urgency

  • Had a colonoscopy completed within 24 months prior to study start.

Participants Must Not:

  • Crohn’s disease

  • Inflammatory bowel disease unclassified

  • Disease of the rectum

  • Inherited immunodeficiency syndrome

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Clinical Trial Resources

Crohn's + Ulcerative Colitis Research

New treatments for Crohn’s Disease and Ulcerative Colitis cannot be developed without clinical trial volunteers. By volunteering to participate, you may be able to make important contributions to scientific research. Each clinical trial is different, but the information provided may help you consider whether a clinical trial may be right for you.

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Clinical Trial Participation: What to Expect

A clinical trial is a scientific study. It helps us learn if a new medicine or treatment works and how it works. Clinical trials can also be called clinical research studies. Learn more about clinical research studies and what to expect when taking part in a clinical trial.