Enrolling

A Study of Mirikizumab (LY3074828) in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT-URGE)

I6T-MC-AMBZ -

A study to investigate bowel urgency in adults with moderately to severely active ulcerative colitis treated with mirikizumab. The study will have 4 periods.

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See if You May Qualify

Answer a few questions to see if you meet key criteria for this study.

Trial Summary

Age Range
≥18 years
Conditions the trial is for
Ulcerative Colitis
What the trial is testing?
Mirikizumab
Could I receive a Placebo?
No
Enrollment Goal
160
Trial Dates
May 17, 2023 - Mar 2025
How long will I be in the trial?
The study will last approximately 36 weeks and include up to 11 visits.
Trial Phase
III

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Have ulcerative colitis (chronic inflammation)

  • Have bowel urgency

  • Had a colonoscopy completed within 24 months prior to study start.

Participants Must Not:

  • Crohn’s disease

  • Inflammatory bowel disease unclassified

  • Disease of the rectum

  • Inherited immunodeficiency syndrome

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Clinical Trial Resources

Crohn's + Ulcerative Colitis Research

To learn more about Crohn's and ulcerative colitis and ongoing clinical trials in this area, visit our Crohn's + Ulcerative Colitis Research page.

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Immunology Research

To learn more about immune system conditions and ongoing clinical trials in this area, visit our Immunology Research page.

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Clinical Trial Information

A clinical trial helps us learn if a new potential medicine or treatment works and how it works. Clinical trials are also called clinical research studies. To learn more about what to expect when taking part in a clinical trial, visit our Clinical Trial Information page.