Immunology Research
To learn more about immune system conditions and ongoing clinical trials in this area, visit our Immunology Research page.
Learn MoreThe main purpose of this study is to determine safety and efficacy of orforglipron compared with insulin glargine in participants with type 2 diabetes and obesity or overweight at increased cardiovascular risk.
Have type 2 diabetes
Be taking a consistent dose of 1 to 3 diabetes drugs by mouth for the last 3 months
Be at high risk of heart or blood vessel diseases, or have kidney disease
Have high blood sugar as measured by hemoglobin A1C (HbA1c at least 7%)
Have type 1 diabetes
Have history of an inflamed pancreas (pancreatitis)
Have history of an inflamed liver (hepatitis)
Have used any weight loss drugs, including herbal or nutritional supplements, within the last 3 months
To learn more about immune system conditions and ongoing clinical trials in this area, visit our Immunology Research page.
Learn MoreA clinical trial helps us learn if a new potential medicine or treatment works and how it works. Clinical trials are also called clinical research studies. To learn more about what to expect when taking part in a clinical trial, visit our Clinical Trial Information page.