Weight Management Research
To learn more about obesity, overweight and ongoing clinical trials in the area, visit our Weight Management Research page.
Learn MoreThis study will investigate the efficacy and safety of once daily oral orforglipron in adult participants with obesity or overweight with weight-related comorbidities.
Have obesity or overweight
If overweight, must also have one of the following: High blood pressure, high cholesterol, obstructive sleep apnea or heart disease
Have at least 1 self-report of an unsuccessful at dietary effort to lose weight
Have Type 1 diabetes, Type 2 diabetes, or any other types of diabetes, history of ketoacidosis, or hyperosmolar state/coma
Have a self-reported change in body weight >5 kg (11 pounds) within 90 days prior to screening
Have family (first-degree relative) or personal history of MTC or MEN2 syndrome
Have had a history of chronic or acute pancreatitis
To learn more about obesity, overweight and ongoing clinical trials in the area, visit our Weight Management Research page.
Learn MoreLearn how Lilly is working with health care partners to improve diversity in our clinical studies.
Watch the VideoA clinical trial helps us learn if a new potential medicine or treatment works and how it works. Clinical trials are also called clinical research studies. To learn more about what to expect when taking part in a clinical trial, visit our Clinical Trial Information page.