A Study of Retatrutide (LY3437943) on Renal Function in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes

The main purpose of this study is to investigate the effect of retatrutide on renal function in participants with overweight or obesity and chronic kidney disease (CKD), with or without Type 2 Diabetes (T2D).

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See if You May Qualify

Answer a few questions to see if you meet key criteria for this study.

Trial Summary

Age Range
≥18 years
Conditions the trial is for
Obesity, Overweight, Chronic kidney disease
What the trial is testing?
Could I receive a Placebo?
Enrollment Goal
Trial Dates
Jul 20, 2023 - Nov 2025
How long will I be in the trial?
The study will lasts around 31 weeks.
Trial Phase

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Be overweight

  • Have no Type 2 diabetes or has Type 2 diabetes and treated with diet and exercise only with stable doses of up to 3 oral diabetic medications

  • Have been diagnosed with CKD

Participants Must Not:

  • Have a change in body weight greater than 11 pounds

  • Have Type 1 Diabetes

  • Have acute or chronic hepatitis

  • Have a history of cancer within 5 years before screening

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Take the Next Step

Complete this Lilly Trial Match questionnaire to find out if this clinical trial may be a good fit for you, or a loved one.
When you press Start Lilly Trial Match, you will answer questions about relevant medical conditions and treatment history. The answers will be compared to some of the key criteria for this trial, called inclusion and exclusion criteria.

If your responses show that the trial may be a good fit, you can:
  • Select which clinical trial site works best for you.
  • Share your details and questionnaire directly with site(s) that allow this.
  • Get contact details for the site(s) of your choice.

Completing the Trial Match questionnaire doesn’t mean that you will be enrolled in a study. There may be more eligibility criteria for the study which are assessed by the Lilly clinical team.

Clinical Trial Resources

Obesity Research

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Diabetes Research

To learn more about diabetes and clinical trials being carried out in this area, visit our Diabetes Research page.

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study. It helps us learn if a new medicine or treatment works and how it works. Clinical trials can also be called clinical research studies. Learn more about clinical research studies and what to expect when taking part in a clinical trial.