Completed Enrollment

A Long-term Safety Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes (ACHIEVE-J)

The purpose of this study is to determine the long-term safety of the study intervention orforglipron as monotherapy or in combination with oral antihyperglycemic medication.

Trial Summary

Age Range
≥18 years
Conditions the trial is for
Type 2 Diabetes
What the trial is testing?
Orforglipron
Could I receive a Placebo?
No
Enrollment Goal
399
Trial Dates
Sep 28, 2023 - Jun 2025
How long will I be in the trial?
The study will last about 58 weeks and may include up to 13 visits.
Trial Phase
III

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Have Type 2 diabetes

  • Have overweight

Participants Must Not:

  • Have Type 1 diabetes

  • Have severe hypoglycemia or hypoglycemia unawareness within the last 6 months prior to screening, or between screening and randomization.

  • Have heart attack, stroke or congestive heart failure within 60 days prior to screening

  • Have pancreatitis

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Clinical Trial Resources

Diabetes Research

To learn more about diabetes and clinical trials being carried out in this area, visit our Diabetes Research page.

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study. It helps us learn if a new medicine or treatment works and how it works. Clinical trials can also be called clinical research studies. Learn more about clinical research studies and what to expect when taking part in a clinical trial.