Diabetes Research
To learn more about diabetes and ongoing clinical trials in this area, visit our Diabetes Research page.
The main purpose of this study is to assess efficacy and safety of orforglipron compared with oral semaglutide in participants with Type 2 diabetes and inadequate glycemic control with metformin.
Have Type 2 Diabetes
Are of Stable Body Weight for at least 90 days prior to screening
Agree to not begin a strict diet or exercise program during the study
Have Type 1 Diabetes
Have a history of ketoacidosis or hyperosmolar state or coma the last 6 months before screening
Have Congestive Heart Failure
Have acute or chronic hepatitis
Have history of cancer or in remission less than 5 years
To learn more about diabetes and ongoing clinical trials in this area, visit our Diabetes Research page.
A clinical trial helps us learn if a new potential medicine or treatment works and how it works. Clinical trials are also called clinical research studies. To learn more about what to expect when taking part in a clinical trial, visit our Clinical Trial Information page.