Enrolling

A Study of Tirzepatide (LY3298176) Once Weekly in Adolescent Participants Who Have Obesity or Overweight With Weight-Related Comorbidities

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The main purpose of this study is to evaluate the safety and efficacy of tirzepatide in adolescents that have obesity or overweight with at least one weight-related comorbidity.

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See if You May Qualify

Answer a few questions to see if you meet key criteria for this study.

Trial Summary

Age Range
12 - 17 years
Conditions the trial is for
Obesity
What the trial is testing?
Tirzepatide
Could I receive a Placebo?
Yes
Enrollment Goal
150
Trial Dates
Oct 16, 2023 - Oct 2026
How long will I be in the trial?
The study will last about 90 weeks and may include up to 25 visits.
Trial Phase
III

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Have been diagnosed with obesity OR overweight with at least 1 weight-related comorbidity (abnormal lipids, high blood pressure, fatty liver disease, sleep apnea, prediabetes or type 2 diabetes)

  • Have not been able to lose weight with healthy diet and physical activity

  • If with Type 2 diabetes mellitus have been treated with either diet and exercise alone or with metformin for at least 90 days prior to screening and have a HbA1c <9.0%

  • Have started puberty

Participants Must Not:

  • Have lost more than 5 kg (11 lbs) in the 90 days before screening

  • Have Type 1 Diabetes

  • Have a family or personal history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia (MEN) Syndrome Type 2

  • Have a history of pancreatitis

  • Have had or plan to have a weight loss surgery during the study

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Clinical Trial Participation: What to Expect

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