Diabetes Research
To learn more about diabetes and ongoing clinical trials in this area, visit our Diabetes Research page.
The main purpose of this study is to determine the safety and efficacy of orforglipron. Participants will have Type 2 Diabetes (T2D) and have inadequate glycemic control with insulin glargine with or without metformin and/or SGLT-2 (sodium-glucose cotransporter-2) inhibitor.
Have Type 2 Diabetes
Be taking a consistent dose of diabetes drug by injection for at least 3 months
May be taking up to 2 diabetes drugs by mouth for at least 3 months
Have a high blood sugar
Have Type 1 diabetes
Have history of an inflamed pancreas (pancreatitis)
Have history of an inflamed liver (hepatitis)
Have congestive heart failure
To learn more about diabetes and ongoing clinical trials in this area, visit our Diabetes Research page.
A clinical trial helps us learn if a new potential medicine or treatment works and how it works. Clinical trials are also called clinical research studies. To learn more about what to expect when taking part in a clinical trial, visit our Clinical Trial Information page.