Enrolling

A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight

The main purpose of this study, performed under a master protocol, is to investigate weight management efficacy and safety with LY3305677 compared with placebo and in adult participants with obesity or overweight.

Enter your city or zip code to find the nearest site

See if You May Qualify

Select a location and then answer a few questions or connect with the study site to see if you meet key criteria for this study.

Trial Summary

Age Range
18 - 75 years
Conditions the trial is for
Obesity
What the trial is testing?
Mazdutide
Could I receive a Placebo?
Yes
Enrollment Goal
165
Trial Dates
Nov 17, 2023 - May 2025
How long will I be in the trial?
The study will last about 62 weeks and may include up to 20 visits.
Trial Phase
II

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Be 18 or the legal age of consent in the jurisdiction in which the study is taking place to 75 years of age inclusive, at the time of signing the informed consent

  • Have criteria met in the master study

Participants Must Not:

  • Have type 2 Diabetes

  • Have pancreatitis, recent heart attack, stroke, or heart failure

Lilly Trial Alerts

Not the right fit? Sign up to receive updates about new trials that are listed or when a new trial site begins enrolling near you.

Clinical Trial Resources

Obesity Research

Click the below button to learn more about obesity research and clinical trials.

Learn More

Driving Diversity in Lilly’s clinical trials

Learn how Lilly is working with health care partners to improve diversity in our clinical studies.

Watch the Video

Clinical Trial Participation: What to Expect

A clinical trial is a scientific study. It helps us learn if a new medicine or treatment works and how it works. Clinical trials can also be called clinical research studies. Learn more about clinical research studies and what to expect when taking part in a clinical trial.