Enrolling

A Study of Mevidalen (LY3154207) in Participants With Alzheimer's Disease

I7S-MC-HBEO -

The main purpose of this study is to look at how safe the study drug (mevidalen) is and whether it works to alleviate symptoms when given to people with mild to moderate Alzheimer Disease dementia. This is done by looking at participants: thinking and memory (cognition), everyday activities and sleep, AD symptoms, physical activity, irritability or anxiety.

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See if You May Qualify

Answer a few questions to see if you meet key criteria for this study.

Trial Summary

Age Range
50 - 80 years
Conditions the trial is for
Alzheimer Disease
What the trial is testing?
Mevidalen
Could I receive a Placebo?
Yes
Enrollment Goal
300
Trial Dates
Aug 26, 2024 - Jan 2026
How long will I be in the trial?
The study is expected to last approximately 26 weeks and may include up to 14 visits.
Trial Phase
II

Key Requirements

Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.

Participants Must:

  • Have Alzheimer’s disease (AD) with gradual and progressive decline in memory function for greater than or equal to 6 months

  • Have a reliable study partner who will participate in the study to support the participant

  • Be males with partners of childbearing potential must agree to abide with provided contraception guidance

Participants Must Not:

  • Have prior central nervous system or psychiatric disease other than AD

  • Have history of cardiovascular or liver disorders

  • Be currently enrolled or intend to enroll in a clinical trial of another investigational product

  • Have suicidal tendencies

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Clinical Trial Resources

Alzheimer's Research

To learn more about Alzheimer’s, memory loss and ongoing clinical trials in this area, visit our Alzheimer’s Disease Research page.

Learn More

Neurodegenerative Disease Research

To learn more about neurological disorders and ongoing clinical trials in the area, visit our Neurological Disorders Research page.

Clinical Trial Information

A clinical trial helps us learn if a new potential medicine or treatment works and how it works. Clinical trials are also called clinical research studies. To learn more about what to expect when taking part in a clinical trial, visit our Clinical Trial Information page.